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Oestrogen receptors or aromatase can be divided into three subtypes, ER, ERО, and ERО which act in similar manners to respond to different levels of different hormones: ERО is activated at high concentrations of estrogen, while ERО does not respond to any levels of estrogen ERО binds estrogen with affinity greater than that of estrogen and is responsible for most of the estrogen-mediated effects of estrogen ER-negative receptors are highly selective for estrogen and are involved in a variety of processes such as|endoftext|Image copyright AFP Image caption The army says it has cleared rebel positions in the village of Khadamey from which heavy fighting was reported Fighting in a village near the north-east Libyan city of Benghazi has left a third of its people missing and wounded, locals say.
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The army and militias known as the national navy have since launched a large-scale offensive to drive the militants from various locations in and around Benghazi. Fighting in Kufra on Friday was continuing amid reports that security forces had launched an operation to push back IS fighters nearby, the Libyan Red Cross said. In Benghazi, at least 10 people have been killed in recent days in clashes. IS's local affiliate, Ansar al-Sharia, is the latest target, say local residents.
Image copyright Reuters Image caption A large number of IS militants are believed to have fled Libya across the border into Egypt On Friday, militants claimed to have taken control of the Benghazi Military Council, the parliament and the central bank.
In response, Libya's interim authorities moved on Saturday to evacuate civilians from areas in the besieged eastern coastal city of Benghazi, where the UN has said it is at risk of being overrun by IS fighters. State news agency LANA said three mosques were closed in the city because the IS fighters had occupied them.
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References 1. Tamoxifen: an overview of management. N Engl J Med (2007) 356: 2039. PMID: 17157927 2. Honein MA, Liu Y, Shigenaga S, et al.
Endocrine therapy versus radiation therapy for breast cancer: are tamoxifen, aromatase inhibitors, and tamoxifen-indazole combination regimens a good strategy. Ann Surg Oncol (2009) 26: 39-45. Available from: http:www.
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